![]() 1 Thus, laboratory analyzers that provide rapid and accurate results are critically necessary. 1 According to the guidelines of the American Association for Respiratory Care (AARC 2013), blood gas and lactate are measured to evaluate the acid-base and oxygenation status of patients, the effectiveness of supplemental oxygen given, early goal-directed therapy in sepsis, patient progress and patient circulation status. Determining these levels is particularly essential in intensive care patient management, as blood gas and lactate levels are utilized as the basis for determining disease severity, evaluating treatments given, and estimating prognosis. Levels of blood gases and lactic acid are important for evaluating the equilibrium between tissue oxygen delivery and demand, as well as the acid-base balance. However, lactate measurement results >8 mmol/L on the i-STAT ® analyzer should be interpreted with caution. This comparison study of pH, pCO 2, pO 2, and lactate measurements between Nova pHOx plus L ® and i-STAT ® analyzers showed good agreement. No significant inter-device variability was observed between the i-STAT ® analyzers. Biases between the benchtop analyzer and the i-STAT ® were not clinically significant, except pH. The results that were beyond the limits were primarily lactate levels >8 mmol/L. In Bland-Altman analysis, ≥95% of the results were within the limits of agreement, with the exception of lactate, which had only 93%. Strong correlations were observed for all test results. Testing of the inter-device variability was done by using three different i-STAT ® devices, and the results were compared statistically. The results of both devices were compared using Pearson or Spearman correlation coefficients and Bland-Altman tests. Each sample was measured for pH, pCO 2, pO 2, and lactate using a Nova pHOx plus L ® benchtop blood gas analyzer in the central laboratory and an i-STAT ® handheld POC device. MethodsĪ cross-sectional study was conducted with a sample size of 100. This study aimed to compare pH, pCO 2, pO 2, and lactate measurements between a POC device and a benchtop blood gas analyzer typically used in a hospital central laboratory, and to evaluate the inter-device variability of the POC device. Point-of-care (POC) testing simplifies and provides rapid blood gas and lactate measurements. ![]() Blood gas analysis and blood lactate measurement have important roles in patient management.
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